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An East-Asian-type cagA Helicobacter pylori Infected Patient with Clinical Manifestation of Gastric Ulcer

Rezkitha, Yudith Annisa Ayu and Miftahussurur, Muhammad and Nusi , Iswan Abbas and Maimunah, Ummi and Adi, Pangestu and Yamaoka , Yoshio (2016) An East-Asian-type cagA Helicobacter pylori Infected Patient with Clinical Manifestation of Gastric Ulcer. Acta Medica Indonesiana, 48 (4). pp. 307-313. ISSN 0125-9326

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        Abstract

        We reported a male, 72 yo, Chinese ethnic with chief complaint black mushy defecation. Physical examination revealed pale on conjunctival palpebra which confirmed as anemia on complete blood count. Gastroduodenoscopy revealed a 3 mm ulcer at the antrum (Forrest stage III). H. pylori infection was positive based on five different test methods (urinary antibody tests, rapid urease test, culture, histology ad immunohistochemistry). Used polymerase chain reaction-based sequencing, we found the patient infected by CagA producing, East-Asian-type cagA and vacA s1m1-strain. Further analysis using 7 housekeeping genes confirmed that the strain categorized in to hspEAsia group. The patient was given continuous intravenous infusions of proton pump inhibitor and standard triple therapy regimens eradication of H. pylori.

        Item Type: Article
        Uncontrolled Keywords: Helicobacter pylori, gastric ulcer, East-Asian-type cagA, vacA
        Subjects: Q Science > QR Microbiology
        R Medicine > R Medicine (General)
        Divisions: Jurnal > Fakultas Kedokteran
        Depositing User: YUDITH ANNISA AYU REZKITHA
        Date Deposited: 14 Aug 2020 12:11
        Last Modified: 18 Nov 2020 11:06
        URI: http://repository.um-surabaya.ac.id/id/eprint/4220

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