Bioactivity of Phytochemicals in Curcuma Domestica on Lymphocyte Cell Count in Mice (Mus Musculus)

Nastiti, Kartikorini and Rahma Widyastuti, S.Si., M.Kes. and Diah Ariana, ST., M.Kes. and Baterun, Kunsah (2022) Bioactivity of Phytochemicals in Curcuma Domestica on Lymphocyte Cell Count in Mice (Mus Musculus). Prosiding : 2nd International Conference of Health Innovation and Technology, 2. pp. 108-115. ISSN 2468-5739

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Abstract

The immune system or immunity is a system that can protect the human body against foreign objects that enter the body. People can maintain their immune system by consuming healthy and nutritious food, exercising regularly, maintaining personal health, taking supplements or immune-boosting vitamins, and consuming traditional herbs, such as juice from the phytochemical Curcuma domestica (turmeric). Curcuma domestica is a tropical plant, and it can find in many parts of Asia, one of which is Indonesia. The main components of the phytochemical Curcuma domestica are curcumin and essential oils. In contrast, the phytochemicals of curcumin and essential oils can boost the immune system because they are proven to increase lymphocyte cells. This study aimed to determine the bioactivity of phytochemicals in Curcuma domestica on the number of lymphocyte cells in mice (Mus musculus). This study was experimental research with the pre and post-test design. The sample used in this study was 32 mice divided into two groups, including control and treatment groups. Data of lymphocyte cells were analyzed using a manual method, namely peripheral blood smear. The data were analyzed using the SPSS (Statistical Program Social Science) application using the independent t-test. The results were p = 0.000 (p 0.05), so Ho was rejected, and Ha was accepted. The results obtained in the control group showed that the average number of lymphocyte cells before treatment was 42.5%, and after treatment was 47.5%. While in the treatment group, the average number of lymphocyte cells before being given the phytochemical extract of Curcuma domestica was 41.75%, and after being given the phytochemical extract of Curcuma domestica was 57.25%. The conclusion is that giving the phytochemical extract of Curcuma domestica affects the number of lymphocyte cells in mice (Mus musculus).

Item Type:	Article
Subjects:	R Medicine > R Medicine (General)
Divisions:	Prosiding > Fakultas Ilmu Kesehatan
Depositing User:	BATERUN KUNSAH KUNSAH
Date Deposited:	30 Mar 2025 09:43
Last Modified:	30 Mar 2025 09:43
URI:	http://repository.um-surabaya.ac.id/id/eprint/10048

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