BIOAKTIFITAS BUNGA SEPATU (Hibiscus rosa-sinensis L.) TERHADAP KADAR KOLESTEROL DARAH MENCIT (Mus musculus) YANG MENGALAMI HIPERKOLESTEROLEMIA DENGAN DIET TINGGI LEMAK

SAMSUDIN, RINZA RAHMAWATI (2017) BIOAKTIFITAS BUNGA SEPATU (Hibiscus rosa-sinensis L.) TERHADAP KADAR KOLESTEROL DARAH MENCIT (Mus musculus) YANG MENGALAMI HIPERKOLESTEROLEMIA DENGAN DIET TINGGI LEMAK. The Journal Of Muhammadiyah Medicl Labortory Technologist, 2 (1). pp. 84-89. ISSN 2597-3681

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Abstract

The purpose of this study was to determine the effect of bioactivity of extract Hibiscus rosa-sinensis L. to blood cholesterol level of mice Mus musculus that experienced hypercholesterolemia with high fat diet. This research is a pure experimental research, using randomized post-test only control group design. Hibiscus rosasinensis L.contains anthocyanin pigment which belongs to flavonoid group that acts as antioxidant. Twenty-eight mice were divided into four groups (K1, K2, K3 and K4). The K1 group was the group that received high fat treatment and aquadest after acclimation. Groups K2, K3, and K4 are treatment groups treated with high-fat diet, septal extract of 1 ml and aquadest after acclimation. High-fat feeding lasts 28 days. During the research has been done weighing the mouse five times. The results showed that giving 1 ml of extract Hibiscus rosasinensis L. for twenty eight days can decrease the cholesterol level of Mus musculus where the value of p < 0.05.

Item Type:	Article
Subjects:	Q Science > QK Botany R Medicine > R Medicine (General)
Divisions:	Jurnal > Fakultas Ilmu Kesehatan
Depositing User:	RINZA RAHMAWATI SAMSUDIN
Date Deposited:	17 Jan 2019 05:42
Last Modified:	17 Jan 2019 05:42
URI:	http://repository.um-surabaya.ac.id/id/eprint/2950

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