HISTOPATHOLOGICAL DESCRIPTION OF THE LUNGS OF MICE (MUSMUSCULUS) THAT WAS GIVEN ASCORBIC ACID

Sari, Yeti Eka Sispita and Artanti, Dita and Azizah, Fitrotin and Kunsah, Baterun (2021) HISTOPATHOLOGICAL DESCRIPTION OF THE LUNGS OF MICE (MUSMUSCULUS) THAT WAS GIVEN ASCORBIC ACID. In: International Conference on Health Politechnic Ministry of Health Surabaya (ICoHPS 2021):Empowering the Health Professionals and Community in Mitigating the Impacts of Covid-19 Pandemic, 6-7 Oktober 2021, Poltekkes Kemenkes Surabaya.

	PDF (Artikel) Download (330kB)
	PDF (Turnitin) Download (1MB)
	PDF (peer review prosiding) Download (1MB)

Abstract

Ascorbic acid or better known strengthening immunity against infection, especially during the current covid 19 outbreak, the people's consumption power of ascorbic acid is extraordinary.The lung is an elastic cone-shaped organ located in the thoracic cavity and is an organ that oftenexperiences pathological abnormalities. An imbalance of oxidants– antioxidants are mutual lyreinforcing and contribute to tissue damage. The purpose of this study was to determine the effect of consuming low doses of ascorbic acidevery day on lung histopathology,especially fibrosis in mice (Mus musculus). This study was an experimental study with post-test only with acontrol design and used 15 mice as samples. Samples were divided into 5 groups consisting of onepositive control group, one negative control group and three different dose groups from theascorbic acid treatment group (0,76mg,0,51 mgdan 0,26 mg in one treatment, here is done 2 times the treatment in one day for 7 days).Data analysis match results to the score table determining the damage in the form fibrosis. The histological structure of the lungs mice fromeach treatment compared to the control. The damage score of each tweet then per group issummed up and averaged. Furthermore, data analysis is carried out using the One Way ANOVA test. In conclusion,study was conducted consumption of ascorbic acid below the dose alsoresulted in damage to the pulmonary organs and the result is the same as not consuming ascorbic acid. Keywords:lungfibrosis,Ascorbicacid,MusMusculus.

Item Type:	Conference or Workshop Item (Paper)
Subjects:	R Medicine > R Medicine (General) R Medicine > RB Pathology
Divisions:	Prosiding > Fakultas Ilmu Kesehatan
Depositing User:	DITA ARTANTI ARTANTI
Date Deposited:	04 Jul 2023 03:57
Last Modified:	04 Jul 2023 03:57
URI:	http://repository.um-surabaya.ac.id/id/eprint/7321

Actions (login required)

View Item