Cardiovascular Disorders and Obstructive Sleep Apnea

Afrita Amalia, Laitupa and Tjondronegoro, R P Soeharsohadi (2020) Cardiovascular Disorders and Obstructive Sleep Apnea. International Journal of Pharmaceutical Research (IJPR), 16 (1). 0975-2366. ISSN 0975-2366

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Abstract

Obstructive sleep apnea (OSA) is associated with an increased risk of hypertension, coronary heart disease, heart failure and arrhythmias. The prevalence and severity of OSA in cardiovascular disease are increase with age. Mechanism of OSA in cardiovascular disorders associated with oxidative stress, sympathetic activation, inflammation, hypercoagulability, endothelial dysfunction, sleep fragmentation and metabolic dysregulation. Although polysomnography is a gold standard diagnostic tool of OSA but it is still expensive, does require questionnaires as a tool for OSA detection. The treatments consist of continuous positive airway pressure (CPAP), oral appliances, surgical and behavioral modification. Keywords: cardiovascular disorders, CPAP, sympathetic nerve activity.

Item Type:	Article
Uncontrolled Keywords:	cardiovascular disorders, CPAP, sympathetic nerve activity
Subjects:	R Medicine > R Medicine (General) R Medicine > RZ Other systems of medicine
Divisions:	Jurnal > Fakultas Kedokteran
Depositing User:	FAKULTAS KEDOKTERAN KEDOKTERAN
Date Deposited:	19 Jan 2024 03:17
Last Modified:	19 Jan 2024 03:17
URI:	http://repository.um-surabaya.ac.id/id/eprint/8624

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