Hubungan Hasil Pemeriksaan HBsAg dengan Kadar Trombosit pada Pasien Hepatitis B di RSUD Haji Provinsi Jawa Timur

Pemeriksaan Hepatitis B Surface Antigen (HBsAg) digunakan sebagai penanda infeksi HBV, sedangkan kadar trombosit dapat mencerminkan kondisi hematologi akibat gangguan fungsi hati. Penelitian ini bertujuan untuk mengetahui hubungan hasil pemeriksaan HBsAg dengan kadar trombosit pada pasien Hepatitis B di RSUD Haji Provinsi Jawa Timur. Penelitian ini menggunakan desain analitik observasional dengan pendekatan cross-sectional retrospektif. Sampel penelitian berjumlah 74 pasien yang dipilih menggunakan teknik total sampling. Data diperoleh dari rekam medis periode Juli 2025–Mei 2026. Pemeriksaan HBsAg dilakukan dengan metode Electrochemiluminescence Immunoassay (ECLIA), sedangkan kadar trombosit diperiksa menggunakan hematology analyzer. Analisis data menggunakan uji korelasi Spearman. Hasil penelitian menunjukkan nilai koefisien korelasi (r) sebesar 0,019 dengan nilai signifikansi (p) sebesar 0,870 (p>0,05), memiliki makna tidak terdapat hubungan antara hasil pemeriksaan HBsAg dengan kadar trombosit. Hal ini dikarenakan kadar trombosit tidak hanya dipengaruhi oleh keberadaan HBsAg, tetapi juga oleh derajat kerusakan hati, stadium penyakit, terapi yang dijalani, serta kondisi klinis pasien.

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Hepatitis B Surface Antigen (HBsAg) testing is used as a marker of HBV infection, while platelet counts can reflect hematological conditions resulting from liver dysfunction. This study aimed to determine the correlation between HBsAg test results and platelet counts in patients with hepatitis B at Haji Regional General Hospital in East Java Province. This study used an observational analytical design with a retrospective cross-sectional approach. The study sample consisted of 74 patients selected using total sampling. Data were obtained from medical records covering the period from July 2025 to May 2026. HBsAg testing was performed using the Electrochemiluminescence Immunoassay (ECLIA) method, while platelet counts were measured using a hematology analyzer. Data analysis used the Spearman correlation test. The results showed a correlation coefficient (r) of 0.019 with a significance value (p) of 0.870 (p > 0.05), indicating that there is no association between HBsAg test results and platelet counts. This is because platelet counts are influenced not only by the presence of HBsAg but also by the degree of liver damage, the stage of the disease, the treatment received, and the patient’s clinical condition.