Fahriani, Lucia (2026) Profil Penggunaan Obat pada Pasien Hypertensive Heart Disease dengan Gagal Jantung. Undergraduate thesis, Universitas Muhammadiyah Surabaya.
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Abstract
Hipertensi kronis dapat berkembang menjadi penyakit jantung hipertensi yang menyebabkan perubahan struktur dan fungsi jantung hingga berkembang menjadi gagal jantung. Salah satu faktor risiko utama gagal jantung adalah hipertensi, dengan angka kejadian yang terus meningkat di seluruh dunia dan berkontribusi terhadap sekitar 45% kematian akibat penyakit jantung. Penelitian ini bertujuan untuk mengetahui profil penggunaan obat pada pasien hypertensive heart disease dengan gagal jantung di Instalasi Rawat Jalan RSUD Haji Provinsi Jawa Timur. Penelitian ini menggunakan desain observasional deskriptif dengan pengumpulan data secara retrospektif dari rekam medis pasien periode Januari–Oktober 2025. Teknik pengambilan sampel menggunakan total sampling, sehingga didapatkan 116 pasien yang memenuhi kriteria inklusi. Data dianalisis secara deskriptif dan disajikan dalam bentuk tabel. Hasil penelitian menunjukkan bahwa golongan obat yang paling banyak digunakan meliputi ARB terutama candesartan sebanyak 98 penggunaan (22,22%) Selanjutnya, golongan diuretik terdiri dari spironolakton sebanyak 89 penggunaan (20,18%) dan furosemid 83 penggunaan (18,82%). Penggunaan beta blocker hanya bisoprolol sebanyak 66 penggunaan (14,97%), sesuai dengan pedoman klinis yang berlaku. Kesimpulan penelitian ini diharapkan dapat menjadi sumber informasi mengenai pola penggunaan obat hypertensive heart disease dengan gagal jantung sehingga dapat dimanfaatkan sebagai bahan pertimbangan dalam evaluasi terapi dan pengembangan mutu layanan kefarmasian di RSUD Haji Provinsi Jawa Timur.
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Chronic hypertension can progress to hypertensive heart disease, causing changes in the structure and function of the heart, which may eventually lead to heart failure. One of the main risk factors for heart failure is hypertension, with incidence rates continuing to rise worldwide and accounting for approximately 45% of deaths from heart disease. This study aimed to determine the drug utilization profile in patients with hypertensive heart disease and heart failure at the Outpatient Installation of RSUD Haji, East Java Province. This study employed a descriptive observational design with retrospective data collection from patients' medical records covering the period of January to October 2025. Using total sampling, 116 patients met the inclusion criteria. Data were analyzed descriptively and presented in the form of tables and distribution diagrams. The results showed that the most commonly used class of medication was ARBs, particularly candesartan, with 98 prescriptions (22.22%). Next, the diuretic class comprised spironolactone with 89 prescriptions (20.18%) and furosemide with 83 prescriptions (18.82%). The use of beta-blockers was limited to bisoprolol, with 66 instances (14.97%), in accordance with current clinical guidelines The findings of this study are expected to serve as a source of information regarding drug utilization patterns in hypertensive heart disease with heart failure, which may be used as a basis for therapy evaluation and the improvement of pharmaceutical care quality at RSUD Haji, East Java Province.
| Item Type: | Thesis (Undergraduate) |
|---|---|
| Uncontrolled Keywords: | hypertensive heart disease, gagal jantung, hipertensi, profil penggunaan obat, RSUD Haji, hypertensive heart disease, heart failure, hypertension, drug utilization profile, RSUD Haji |
| Subjects: | R Medicine > RC Internal medicine R Medicine > RM Therapeutics. Pharmacology |
| Divisions: | 04. Fakultas Ilmu Kesehatan > Farmasi |
| Depositing User: | LUCIA FAHRIANI |
| Date Deposited: | 22 Sep 2026 04:27 |
| Last Modified: | 22 Sep 2026 04:27 |
| URI: | https://repository.um-surabaya.ac.id/id/eprint/14187 |
