Analisis Hitung Jenis Leukosit akibat Paparan Kebisingan Sound Horeg pada Rattus norvegicus

Syafitri, Ladya kahfidatur (2026) Analisis Hitung Jenis Leukosit akibat Paparan Kebisingan Sound Horeg pada Rattus norvegicus. Applied Bachelor thesis, Universitas Muhammadiyah Surabaya.

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Abstract

Latar belakang Kebisingan sound horeg merupakan sumber suara berintensitas tinggi yang berpotensi menimbulkan stres fisiologis dan memengaruhi profil hematologi. Salah satu parameter hematologi yang dapat digunakan untuk menilai respons tubuh terhadap paparan kebisingan adalah hitung jenis leukosit. Perubahan jumlah dan hitung jenis leukosit dapat menjadi tanda adanya gangguan pada tubuh secara fisik atau penyakit. Tujuan penelitian ini adalah mengetahui perbandingan hitung jenis leukosit pada Rattus norvegicus yang dipapar kebisingan sound horeg dan yang tidak dipapar. Metode penelitian menggunakan desain eksperimental dengan metode true experimental dan rancangan post-test only control group design. Analisis data menggunakan uji Mann–Whitney U untuk eosinofil, basofil, dan neutrofil serta Independent Samples t-test untuk limfosit dan monosit. Hasil uji statistic parametrik dan non parametrik menunjukkan tidak terdapat perbedaan yang signifikan antara kelompok kontrol dan perlakuan pada eosinofil, basofil, neutrofil, limfosit dan monosit P>0.05. Meskipun demikian, kelompok perlakuan menunjukkan kecenderungan peningkatan persentase eosinofil dan limfosit serta penurunan persentase basofil, neutrofil, dan monosit dibandingkan kelompok kontrol. Kesimpulan paparan kebisingan sound horeg tidak memberikan pengaruh yang signifikan terhadap hitung jenis leukosit pada Rattus norvegicus, namun menunjukkan kecenderungan perubahan proporsi beberapa jenis leukosit sebagai respons fisiologis terhadap paparan kebisingan.

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Background: “Sound Horeg” noise is a source of high-intensity sound that can cause physiological stress and alter the haematological profile. One haematological parameter that can be used to assess the body’s response to noise exposure is the leukocyte differential count. Changes in the number and differential count of leukocytes can indicate physical disturbances in the body or disease. The purpose of this study is to determine the comparison of leukocyte differential counts in Rattus norvegicus exposed to noise and those not exposed. The research used an experimental design with a true experimental and a posttest-only control group design. Data analysis used the Mann–Whitney U test for eosinophils, basophils, and neutrophils, and the Independent Samples t-test for lymphocytes and monocytes. The results of the parametric and non-parametric statistical tests showed no significant differences between the control and treatment groups in eosinophils, basophils, neutrophils, lymphocytes, and monocytes (P>0.05). However, the treatment group showed a tendency toward increases in the percentages of eosinophils and lymphocytes and decreases in the percentages of basophils, neutrophils, and monocytes compared with the control group. Conclusion: Exposure to sound-induced noise does not have a significant effect on the leukocyte differential count in Rattus norvegicus, but it shows a tendency to change the proportion of several types of leukocytes as a physiological response to noise exposure.

Item Type: Thesis (Applied Bachelor)
Uncontrolled Keywords: sound horeg, kebisingan, hitung jenis leukosit, Rattus norvegicus, hematologi, sound horeg, noise, leukocyte differential count, Rattus norvegicus, hematology.
Subjects: Q Science > QL Zoology
R Medicine > R Medicine (General)
R Medicine > RB Pathology
Divisions: 04. Fakultas Ilmu Kesehatan > STr. Teknologi Laboratorium Medis
Depositing User: Ladya Kahfidatur Syafitri
Date Deposited: 10 Nov 2026 01:47
Last Modified: 10 Nov 2026 01:47
URI: https://repository.um-surabaya.ac.id/id/eprint/15600

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