Analisis Reaksi Imunitas Seluler pada Santri yang Melaksanakan Salat Tahajud di Pondok Pesantren Modern As-Sholihin Surabaya

Latar belakang penelitian ini adalah tingginya angka stres dan gangguan kesehatan mental pada remaja, termasuk santri, yang dapat meningkatkan kadar hormon kortisol sehingga menurunkan sistem imun, khususnya imunitas seluler. Shalat tahajud sebagai ibadah sunnah diyakini memiliki manfaat psikologis dan fisiologis yang dapat menurunkan stres serta berpotensi meningkatkan respons imun melalui peningkatan jumlah limfosit. Tujuan penelitian ini adalah untuk menganalisis hubungan pelaksanaan shalat tahajud dengan reaksi imunitas seluler pada santri di Pondok Pesantren Modern As-Sholihin Surabaya. Metode penelitian yang digunakan adalah observasional analitik dengan desain cross-sectional. Sampel penelitian berjumlah 30 santri yang dipilih menggunakan teknik purposive sampling. Data pelaksanaan shalat tahajud diperoleh melalui kuesioner, sedangkan reaksi imunitas seluler dinilai berdasarkan jumlah limfosit menggunakan pemeriksaan hematology analyzer. Analisis data dilakukan menggunakan uji Pearson dengan tingkat kemaknaan p<0,05. Hasil penelitian menunjukkan bahwa sebagian besar responden memiliki pelaksanaan shalat tahajud kategori cukup (66,7%) dan kadar limfosit normal (80%). Hasil uji Pearson menunjukkan nilai signifikansi sebesar 0,058 (p<0,05), yang berarti tidak terdapat hubungan yang bermakna antara pelaksanaan shalat tahajud dengan kadar limfosit sebagai indikator reaksi imunitas seluler pada santri. Kesimpulan penelitian ini adalah tidak terdapat hubungan antara pelaksanaan shalat tahajud dengan reaksi imunitas seluler pada santri di Pondok Pesantren Modern As-Sholihin Surabaya. Sehingga, kadar limfosit dalam darah kemungkinan lebih dipengaruhi oleh faktor fisiologis lain seperti status nutrisi, aktifitas fisik, dan kualitas tidur secara keseluruhan.

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Background: This study is motivated by the high prevalence of stress and mental health issues among adolescents, including students at Islamic boarding schools, which can elevate cortisol levels and consequently impair immune system function, particularly cellular immunity. Tahajjud prayer, a voluntary act of worship, is believed to offer psychological and physiological benefits that reduce stress and potentially boost immune responses by increasing lymphocyte counts. Objective: The objective of this study was to analyze the relationship correlation between the practice of Tahajjud prayer and cellular immune responses among students at the As-Sholihin Modern Islamic Boarding School in Surabaya. Method: An observational analytic method with a cross-sectional design was employed. The study sample consisted of 30 students selected via purposive sampling. Data on Tahajjud prayer practices were collected through questionnaires, while cellular immune responses were assessed based on lymphocyte counts using a hematology analyzer. Data analysis was performed using the Pearson test with a significance level of p < 0.05. Results: The results indicated that the majority of respondents fell into the “moderate” category for Tahajjud prayer practice (66.7%) and exhibited normal lymphocyte levels (80%). The Pearson test yielded a significance value of 0.058 (p > 0.05), indicating no significant relationship between the practice of Tahajjud prayer and lymphocyte levels used here as an indicator of cellular immune response among the students. Conclusion: The study concluded that there is no correlation between the practice of Tahajjud prayer and cellular immune responses among students at the As-Sholihin Modern Islamic Boarding School in Surabaya; thus, blood lymphocyte levels are likely influenced more by other physiological factors such as nutritional status, physical activity, and overall sleep quality.