Phytochemical Screening and Evaluation of Red Ginger Extracts on Aphrodisiac Activity

Subhan, Rullyansyah and Fuad, Muzakky and Karima, samlan and Ria, Hanistya and Ellies, Tunjung SM. (2022) Phytochemical Screening and Evaluation of Red Ginger Extracts on Aphrodisiac Activity. Gac Med Caracas, 130 (1). pp. 143-148. ISSN 2774-2318

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Abstract

Introduction: One of the breeding processes is influenced by reproduction factors. Herbal therapy can relieve male infertility, such as red ginger. This study aimed to determine the effect of red ginger extract on aphrodisiac activity. Methods: This study was designed to evaluate the effect of red ginger extract on aphrodisiac activity in Wistar rats. Twenty-five male Wistar rats and fifteen two-month-old females weighing 150-200 g were purchased and placed in cages at the Faculty of Health Sciences, University of Muhammadiyah Surabaya. Wistar rats were given light and dark cycles for 12 hours, fed pellet starter broiler, and drank water ad libitum. Mice were acclimatized for 14 days and randomly divided into five groups A, B, C, D, and E. Groups B, C, and D were the treatment groups, while groups A and E were negative and positive controls, each with five rats. in each group and each kept singly in a separate cage. Groups A and E received 1 mL of distilled water and 5 mg of sildenafil citrate orally for the positive control group. Groups B, C, and D received red ginger extract suspension orally at doses of 100, 200, and 300 mg/kg, respectively, between 9:00 - and 10:00 daily for 21 days. Female mice were paired with male mice in a 1:1 ratio, and mating behaviour was recorded. Results: Male rats in groups C and E each showed a significant increase (p < 0.05) in mounting frequency (MF), intromission frequency (IF), and ejaculatory frequency (EF). Conclusion: Red ginger extract has activity as an aphrodisiac, but it is necessary to conduct tests related to toxicity tests. Keywords: Aphrodisiac, mating, rat, red ginger, sex stimulant.

Item Type:	Article
Subjects:	R Medicine > RS Pharmacy and materia medica
Divisions:	Jurnal > Fakultas Ilmu Kesehatan
Depositing User:	ELLIES TUNJUNG SARI
Date Deposited:	05 Jun 2023 03:30
Last Modified:	05 Jun 2023 03:30
URI:	http://repository.um-surabaya.ac.id/id/eprint/7092

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