Phytochemical Screening and Evaluation of Red Ginger Extracts on Aphrodisiac Activity

Introduction: One of the breeding processes is
influenced by reproduction factors. Herbal therapy
can relieve male infertility, such as red ginger. This
study aimed to determine the effect of red ginger extract
on aphrodisiac activity.
Methods: This study was designed to evaluate the
effect of red ginger extract on aphrodisiac activity in
Wistar rats. Twenty-five male Wistar rats and fifteen
two-month-old females weighing 150-200 g were
purchased and placed in cages at the Faculty of Health
Sciences, University of Muhammadiyah Surabaya.
Wistar rats were given light and dark cycles for 12
hours, fed pellet starter broiler, and drank water ad
libitum. Mice were acclimatized for 14 days and
randomly divided into five groups A, B, C, D, and E.
Groups B, C, and D were the treatment groups, while
groups A and E were negative and positive controls,
each with five rats. in each group and each kept
singly in a separate cage. Groups A and E received
1 mL of distilled water and 5 mg of sildenafil citrate
orally for the positive control group. Groups B, C,
and D received red ginger extract suspension orally
at doses of 100, 200, and 300 mg/kg, respectively,
between 9:00 - and 10:00 daily for 21 days. Female
mice were paired with male mice in a 1:1 ratio, and
mating behaviour was recorded.
Results: Male rats in groups C and E each showed a
significant increase (p < 0.05) in mounting frequency
(MF), intromission frequency (IF), and ejaculatory
frequency (EF).
Conclusion: Red ginger extract has activity as an
aphrodisiac, but it is necessary to conduct tests related
to toxicity tests.
Keywords: Aphrodisiac, mating, rat, red ginger, sex
stimulant.