Dilema Penggunaan Aspirin dan Proton Pump Inhibitor (PPI) Pada Pasien Gastroesophageal Reflux Disease Dengan Coronary Artery Disease (CAD)

Prahastutik, Rizkia Hani and Airlangga, Muhammad Perdana and Rezkitha, Yudith Annisa Ayu and Irawati, Detti Nur (2021) Dilema Penggunaan Aspirin dan Proton Pump Inhibitor (PPI) Pada Pasien Gastroesophageal Reflux Disease Dengan Coronary Artery Disease (CAD). Journal of Islamic Medicine, 5 (1). pp. 33-40. ISSN e-ISSN: 2550-0074

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Abstract

Background: Gastroesophageal Reflux Disease (GERD) This often occurs in people with Coronary Artery Disease (CAD) with complaints of chest pain.. Hence antiplatelet drugs are combined withProton Pump Inhibitors (PPIs) for the prevention of aspirin side effects and the treatment of GERD itself. Due to the side effects of gastrointestinal bleeding caused by aspirin, Proton Pump Inhibitors (PPIs) can also have the effect of reducing aspirin bioavailability, thereby reducing the action of aspirin. Objectif :To analyze Gastroesophageal Reflux Disease (GERD) patients with Coronary Artery Disease (CAD) treatment dilemma. Methods : Published scientific articles on patients Gastroesophageal Reflux Disease (GERD) with Coronary Artery Disease (CAD) searchable using keywords Gastroesophageal Reflux Disease, Coronary Artery Disease, Antiplatelet, Proton Pump Inhibitors. by obtaining the number of articles as many as 1144877 and having been screened according to the inclusion criteria to 31 journals. Results: In Gastroesophageal Reflux Disease (GERD) patients with Coronary Artery Disease (CAD) Proton Pump Inhibitors (PPIs) are often combined with antiplatelet agents that have been shown to effectively reduce the risk of gastrointestinal complications in patients. However, in some studies Proton Pump Inhibitors (PPIs) administration will reduce the efficacy effect of aspirin antiplatelet Conclusion : The use of PPI in Gastroesophageal Reflux Disease (GERD) is recommended for short-term use, because long-term use of Proton Pump Inhibitors (PPIs) increases the risk of myocardial infarction, renal failure, and dementia. As well as consideration of the risks and benefits by examining the risk factors of ganstrointestinal

Item Type:	Article
Uncontrolled Keywords:	Antiplatelet, Coronary Artery Disease, Gastroesophageal Proton Pump Inhibitors Reflux Disease,
Subjects:	L Education > L Education (General) R Medicine > R Medicine (General)
Divisions:	Jurnal > Fakultas Kedokteran
Depositing User:	DETTI NUR IRAWATI
Date Deposited:	21 Jul 2023 04:17
Last Modified:	21 Jul 2023 04:17
URI:	http://repository.um-surabaya.ac.id/id/eprint/7363

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