Sensitivity of tekelan leaves (Chromolaena odorata) on the growth of salmonella

3254 Bali Medical Journal 2023; 12(3): 3254-3256 | doi: 10.15562/bmj.v12i3.4395ORIGINAL ARTICLE
ABSTRACT
Sensitivity of
tekelan leaves (Chromolaena odorata) on
the growth of salmonella
Yeti Eka Sispita Sari1, Fitrotin Azizah1*, Dita Artanti1, Anindita Riesti Retno Arimurti1,
Andreas Putro Ragil Santoso2
Introduction: Inappropriate use of antibiotics can lead to an increase in side effects and antibiotic toxicity. One of the natural
herbal ingredients as an alternative treatment for Salmonella infection is the tekelan leaves plant (Chromolaena odorata).
The purpose of this study was to determine the effect of boiled tekelan leaves (Chromolaena odorata) leaves on the growth
of Salmonella.
Methods: The study was a post-test-only control group design, which examined the effects of tekelan leaf (Chromolaena
odorata) extract against the growth of Salmonella at concentrations of 20%, 40%, 60%, 80%, and 100%. The study’s
independent variables were the concentrations of ethanol extract from tekelan leaves at 20%, 40%, 60%, 80%, and 100%.
The bound variable in this study is the growth of Salmonella typhi based on minimal obstructive power and minimal
killing power. Microsoft Excel 2020 was used to examine the data and determine how the effects of each therapy at each
concentration differed from one another.
Results: Results of treatment with tekelan leaves decoction showed that concentrations of 20%, 40%, 60%, 80%, and
100% of tekelan leaves decoction (Chromolaena odorata) did not form an inhibitory zone, so it was said to be in the resistant
category.
Conclusion: The concentration of the boiled leaves of tekelan leaves (Chromolaena odorata) showed no effect on the growth
of Salmonella.
Keywords: Salmonella, tekelan leaves (Chromolaena odorata), herbal medicine, antibiotic.