Perbedaan Follicle Oocyte Index pada Pasien In Vitro Fertilisation dengan Kriteria POSEIDON 3 dan 4 yang Mendapat Ministimulasi dibandingkan Stimulasi Gonadotropin

Latar Belakang: In Vitro Fertilisation (IVF) merupakan metode penanganan infertilitas yang keberhasilannya dipengaruhi oleh kualitas dan kuantitas oosit. Follicle Oocyte Index (FOI) menjadi indikator penting dalam menilai respons ovarium terhadap stimulasi. Tujuan: Untuk mengetahui perbedaan FOI pada pasien IVF dengan kriteria Poseidon 3 dan 4 yang mendapat ministimulasi dibanding stimulasi Gonadotropin. Metode: Penelitian ini menggunakan desain analitik observasional dengan pendekatan cross-sectional. Data diperoleh dari rekam medis pasien IVF di ASHA IVF RS PHC Surabaya dari Juni 2022 hingga Juni 2024 dan analisis dilakukan menggunakan uji Chi-square. Hasil: Dari 107 pasien, karakteristik sampel penelitian terdiri dari usia, AMH, AFC, FSH, LH, Estrogen, dan Progesteron. Hasil dari analisis bivariat dengan uji Chi-square menunjukan nilai p-value 0,088 (p = <0.005) yaitu tidak terdapat perbedaan signifikan antara FOI yang mendapat ministimulasi dan stimulasi gonadotropin di ASHA IVF RS PHC Surabaya. Kesimpulan: Pasien Poseidon 3 dan 4 yang mendapat Ministimulasi atau Stimulasi Gonadotropin hasil FOI nya sama.

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Background: In Vitro Fertilization (IVF) is a method of infertility treatment whose success is influenced by the quality and quantity of oocytes. The Follicle Oocyte Index (FOI) is an important indicator in assessing ovarian response to stimulation. Objective: To determine the difference in FOI among IVF patients with Poseidon group 3 and 4 criteria who received mild stimulation compared to those who received gonadotropin stimulation. Methods: This study used an observational analytic design with a cross-sectional approach. Data were obtained from the medical records of IVF patients at ASHA IVF PHC Hospital Surabaya from June 2022 to June 2024, and analysis was performed using the Chi-square test. Results: Out of 107 patients, the sample characteristics included age, AMH, AFC, FSH, LH, Estrogen, and Progesterone levels. Bivariate analysis using the Chi-square test showed a p-value of 0.088 (p < 0.005), indicating no significant difference in FOI between patients who received mild stimulation and those who received gonadotropin stimulation at ASHA IVF PHC Hospital Surabaya. Conclusion: Poseidon group 3 and 4 patients who underwent either ministimulation or gonadotropin stimulation had similar FOI outcomes.