Hubungan Neutrophil-to-Lymphocyte Ratio (NLR) dengan Luaran Pasien Ventilator Associated Pneumonia (VAP) di Rumah Sakit Siti Khodijah Muhammadiyah Cabang Sepanjang

Faradisa, Istna (2025) Hubungan Neutrophil-to-Lymphocyte Ratio (NLR) dengan Luaran Pasien Ventilator Associated Pneumonia (VAP) di Rumah Sakit Siti Khodijah Muhammadiyah Cabang Sepanjang. Undergraduate thesis, Universitas Muhammadiyah Surabaya.

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Abstract

Masalah : Ventilator-Associated Pneumonia (VAP) merupakan pneumonia nosokomial dengan tingkat mortalitas tinggi. Kejadian mortalitas yang tinggi pada VAP dapat diminimalisir apabila proses inflamasi parenkim paru dapat diketahui dengan lebih cepat dan mudah. Salah satu biomarker proses inflamasi VAP adalah NLR. Beberapa penelitian menunjukkan NLR merupakan indikator yang sensitive untuk berbagai kondisi infeksi dan inflamasi. Namun, belum banyak penelitian yang relevan terkait NLR sebagai biomarker VAP secara khusus. Tujuan : Mengetahui hubungan NLR dengan luaran pasien VAP di Rumah Sakit Siti Khodijah Sepanjang. Metode : Penelitian ini merupakan penelitian observasional analitik dengan pendekatan cross-sectional.. Teknik pengambilan sampel menggunakan teknik consecutive sampling dari tahun 2022-2024, didapatkan 14 sampel rekam medis pasien VAP. Uji statistika penelitian ini menggunakan uji korelasi Spearman rho. Hasil : Usia sampel pada penelitian ini sebagian besar berasal dari kelompok usia 60-69 tahun (50,0%). Terdapat kesamaan jumlah data dari sampel berjenis kelamin laki-laki dan perempuan. Nilai NLR sampel hampir seluruhnya tinggi, yaitu sebanyak 13 sampel (92,9%). Distribusi luaran sampel VAP didominasi sampel meninggal yaitu sebesar 8 sampel (57,1%). Tidak terdapat hubungan signifikan secara statistik antara NLR dengan luaran pasien VAP pada penelitian ini (p=0,264, CI 95% (-0,270 – 0,735)). Namun nilai koefisien korelasi penelitian ini menunjukkan arah positif atau searah (r=0,320). Kesimpulan : Tidak ada hubungan yang signifikan secara statistik antara NLR dengan luaran pasien VAP di Rumah Sakit Siti Khodijah Muhammadiyah Sepanjang.

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Background : Ventilator-associated pneumonia (VAP) is a nosocomial pneumonia with a high mortality rate. The high mortality rate in VAP can be minimized if the inflammatory process of the lung parenchyma can be identified more quickly and easily. One of the biomarkers of the VAP inflammatory process is NLR. Several studies have shown that NLR is a sensitive indicator for several infectious and inflammatory conditions. However, there have not been many relevant studies on NLR as a VAP biomarker specifically. Objective : To identify the correlation between NLR and outcomes of patients with VAP at Siti Khodijah Muhammadiyah Sepanjang Hospital. Methods : This study is an analytical observational study with a cross-sectional method. The sampling technique used was consecutive sampling, which obtained 14 samples of VAP patient medical records from 2022-2024. The statistical test used was the Spearman rho correlation test. Result : The Age of sample majority came from 60-69 years (50%). Data male and female samples are equal. The NLR values of the samples were almost all high, with 13 samples (92.9%). Eight deceased samples (57.1%) dominated the distribution of VAP sample outcomes. This study did not find a statistically significant relationship between NLR and VAP patient outcomes (p = 0.264, 95% CI (-0,270 – 0,735)). However, the correlation coefficient value of this study showed a positive direction (r = 0.320). Conclusion : There is no statistically significant correlation between NLR and the outcome of VAP patients at Siti Khodijah Muhammadiyah Sepanjang Hospital.

Item Type: Thesis (Undergraduate)
Uncontrolled Keywords: NLR, VAP, Luaran pasien VAP, Pasien VAP Rumah Sakit Siti Khodijah Muhammadiyah Sepanjang, NLR, VAP, Outcomes of VAP, VAP Patients at Siti Khodijah Muhammadiyah Sepanjang Hospital
Subjects: R Medicine > RA Public aspects of medicine
R Medicine > RB Pathology
R Medicine > RC Internal medicine
Divisions: 05. Fakultas Kedokteran > Pendidikan Dokter
Depositing User: Magang Repository_01
Date Deposited: 29 Jan 2026 06:59
Last Modified: 29 Jan 2026 07:13
URI: https://repository.um-surabaya.ac.id/id/eprint/11014

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