Thyroid Crisis and Hyperosmolar Hyperglycemic State in a Hyperthyroid Patient

Hyperthyroidism is one form of thyrotoxicosis caused by excess synthesis and thyroid hormone secretion by
the thyroid gland. Thyroid crisis is a life-threatening hyperthyroid exacerbation, characterized by
decompensation of one or more organ systems and hyperosmolar hyperglycemic state (HHS) characterized
by hyperglycemia, hyperosmolality, and dehydration without ketoacidosis. Cases of thyroid and HHS crises
are rarely found in hyperthyroid patients. The purpose of this case report is to describe symptoms for
diagnosis, therapy, and prognosis of hyperthyroid patients with thyroid and HHS crises. We reviewed the
literature and describe hyperthyroid manifestations with thyroid crisis and HHS. A 30-year-old woman
found an increase in pulse rate, body temperature, respiration rate, enlarged diffuse solid (50 cm3), mobile,
dry skin, 600 cc / 4-hour urine production, Burch-Wartofsky score of 95, elevated blood glucose, and
osmolarity blood. Therapies were given under the formula TS 416688-24-6 for thyroid crisis, rehydration,
and management of blood sugar levels was used for HHS. The patient showed improvement after five days
of care with a good prognosis. It was concluded that thyroid crisis and HHS have a poor prognosis because
of the high mortality rates. Identification and the correct diagnosis could improve the prognosis of the case.