Uji Aktivitas Anti Bakteri Dari Formula Ekstrak Daun Ciplukan (Physalis angulata L.) dan Batang Kayu Manis (Cinnamomum burmannii) Secara In Vitro Test

Ciplukan leaves (Physalis angulata L.) and Cinnamon
(Cinnamomum burmannii) are one of medicinal plants that
contain antibacterial active compounds. This study aims to
determine the antibacterial activity of the combination formula
between extracts of ciplukan leaves and cinnamon sticks
against the growth of Staphylococcus aureus bacteria in Vitro.
Ciplukan leaves (Physalis angulata L.) and cinnamon
(Cinnamomum burmannii) were extracted by the maceration
method with 70% ethanol. Ciplukan leaf extract (Physalis
angulata L.) and cinnamon (Cinnamomum burmannii) were
tested against Staphylococcus aureus bacteria using the good
method by measuring transmittance on a spectrophotometer at
a wavelength of 580 nm with 3 repetitions, 100 ppml standard
Septromycin solution as control positive and aquadest as a
negative dick. Inhibition zone diameter of ciplukan leaf extract
(Physalis angulata L.) x̄ = 12.46 mm, Cinnamon Extract
(Cinnamomum burmannii) x̄ = 18.93 mm, while in the
formulation group x̄ = 22.45 mm. One-way analysis of variance
(ANOVA) of these data compared with Streptomycin activity
(positive control) showed significant inhibitory activity by the
formulated extract against S. aureus.