Stimulus from the activator agent Solanum melongena L. on sperm quality through the lipid profile of Rattus norvegicus with hyperlipid induction

Introduction: A high-fat diet and obesity, promoted
by an unhealthy lifestyle, affect the structure of
spermatozoa. The study aims to determine the effect
of using purple eggplant on improving lipid profile
and sperm quality as an alternative to traditional
medicine of Rattus norvegicus. Methods: This type
of research is a laboratory experiment using a post�test with a control group design. Twenty-eight Rattus
norvegicus were divided into four groups. The number
of spermatozoa was calculated by sucking the sperm
stock solution using a hemocytometer suction. Results:
The high cholesterol and distilled water (G1), high
cholesterol and purple eggplant 100 mg/kg BW (G2),
and high cholesterol and purple eggplant 200 mg/kg
BW (G3) groups had higher body weight compared to
the standard feed and distilled water (G0) group. The
G1 group had the highest body weight (136.25±0.901
grams) and cholesterol levels (168.13±1.797 mg/dL).
Moreover, G3 group (159.38±1.253 mg/dL) had lower
cholesterol levels compared to G2 group (152.25±10.31
mg/dL). The G3 group (35.00x106
±0.500) had the
highest mean sperm count, followed by G1, G2, and
G0 groups (33.25x106
± 0.675, 32.75x106
±0.366,
31.38x106
±0.680, respectively). Conclusion: The
purple eggplant extract was able to reduce cholesterol
levels and increase sperm count.
Keywords: Purple eggplant, body weight, cholesterol
levels, sperm count