Effect Of Peel Extract and Crown of Pineapple (Ananas comosus L.Merr) on The Growth of Trichophytonrubrum Fungus

Trichophyton rubrum is a fungal species that often infects human skin. Treatment in healing these infections usually uses chemical drugs sold in the market such as ketoconazole drugs. These chemical drugs have many side effects, so there is a need for natural remedies that can replace chemical drugs. Pineapple peel and leaf crown (Ananas comosusL. Merr) is a type of fruit part which is a residual waste and is not used. The content in the peel and crown of pineapple leaves (Ananas comosusL. Merr) are flavonoids, alkaloids, saponins, and tannins which have the content to inhibit the growth of the fungus Trichophyton rubrum. The purpose of this study was to determine whether there was an effect of extracts of the peel and crown of pineapple leaves (Ananas comosusL. Merr) on the growth of the fungus Trichophyton rubum. This research includes experimental research using the Kirby-Bauer method or disc paper. The treatments in this study used concentrations of 25%, 50%, 75% extract of pineapple peel and leaf crown (Ananas comosusL. Merr), negative control (0%) and positive control (ketoconazole). Based on the Mann-Whitney test with a significant provision of 0.05, it was found that there were differences in each treatment. These results indicate that there is an effect of extracts of the peel and crown of pineapple leaves (Ananas comosusL. Merr) on the growth of the fungus Trichophyton rubrum and the best concentration of inhibition zone is 75%.

Keyword : Trichophyton rubrum, peel and crown extract of pineapple (Ananas comosusL. Merr).