PENGARUH PEMBERIAN SARI TEBU TERHADAP KADAR KOLESTEROL DARAH PADA MENCIT

Sugarcane (Saccharum officinarum L.) is a plant known by the
public as a refreshing drink that tastes sweet and the price is quite
economical and readily available. Sugarcane contains octacosanol
compounds that can lower cholesterol levels in the blood. Excessive
cholesterol (hypercholesterolemia) a threat that is feared because as
one of the causes of coronary heart disease (CHD) and stroke. The
purpose of this study was to analyze the levels of cholesterol in mice,
to analyze cholesterol levels in mice after the administration of sugar
cane juice, to analyze the effect of sugar cane juice on cholesterol
levels in mice. This type of research conducted by a group of
experimental methods with populations of mice (Mus musculus) were
obtained from farms Bojonegoro. The research sample selected by
criteria mice aged 2-3 months, weighing between 20-40 grams of the
male sex, the amount of sample used two groups of mice, each group
consisted of 16 mice. From the results of blood cholesterol levels in
mice after the administration of sugar cane juice, it is known that the
average cholesterol level in the control group was 148.8750 mg / dl
and value - average blood cholesterol treatment group was 118.2500
mg / dl. Statistically analyzed using a paired t test t value -3.799
obtained with significant value. (p) = 0.001 which is less than 0.05
then there is the effect (Ho is rejected) (t = -2.040 table). So we can
conclude there is the effect of sugar cane juice on blood cholesterol
levels in mice.
Keywords : Sugarcane, blood cholesterol levels