Uji Toksisitas Akut Kulit Kentang (Solanum tuberosum L.) Terhadap Larva Artemia salina Leach Dengan Metode BSLT (Brine Shrimp Lethality Test)

Potatoes are one of the vegetables that contain substances that
are important for the formation of body tissues, such as protein and
fat. Potatoes also form red blood cells or hemoglobin (Ca, P and Fe).
In Indonesia tend to process potatoes using only meat. The skin is
removed, even though the nutritional content of the skin is five times
greater than the meat. Potato peels that supply querestin, antioxidants
and flavonoids that act as free radical acceptors. (Free radicals are
reactive molecules that cause damage to the body that can lead to
diseases such as heart disease and cancer) in the skin of potatoes
found also effective antioxidants, chlorogenic acid. Potato skin is also
proven to increase hemoglobin levels (Khomsan, A, 2009). However,
that does not mean potato skin does not have adverse side effects, if
the use is not appropriate. In order to use it optimally, you need to
know enough information about the advantages and disadvantages and
the possibility of abuse. However, the level of toxicity from potato
skin is still unknown. Brine Shrimp Lethality Test (BSLT) is one of
the oxicity test methods that is widely used in tracing bioactive
compounds that are toxic from natural materials. This research is an
experimental research with post test-only control group design
approach. Treatment with giving potato skin juice to Artemia salina
Leach larvae with the aim to determine the potential of plant
biological activity based on the toxicity of secondary metabolites
contained in it, and at the same time as the initial screening test of
anticancer activity of chemical compounds in potato skin juice. The
results showed the LC50 value was at a concentration of 0.5% to 1%
and based on the results of SPSS 21 analysis with probit analysis
obtained LC50 price data of 0.746 gr / ml (7460 μgr / ml), based on
the results of research and data analysis it can be concluded that potato
skin has an LC50 value at a concentration of 0.746 gr / ml (7460 µgr /
ml). With an LC50 price of more than 1000 µg / ml according to the
BST method the potato skin does not have the potential for toxicity so
the skin of the potato has the potential as an alternative to increasing
hemoglobin levels.
Keywords: potato skin, toxicity, BSlT