Infectious diseases caused by Staphylococcus aureus are a health problem in Indonesia. Antibiotics can be used as the treatment, but currently Staphylococcus aureus is resistant to antibiotics. Therefore,it is necessary to find alternative medicine. One of the plants that has characteristics to be
used as herbal medicine is Breadfruit leaves. The purpose of this study was to determinethe effect of concentration on breadfruit leaf juice which can
inhibit the growth of Staphylococcus aureus bacteria. This type of research is experimental. The study population was pure Staphylococcus aureus bacteria on NAS (Nutrient Agar Slant) media. The sample in this study was pure Staphylococcus aureus transferred from pure culture media (NAS), while the number of repetitions of the sample was 5 times the treatment,
in this study wereP1 (100%), P2 (75%), P3(50%), P4 (25%), P5(0%). Data
on the growth of Staphylococcus aureus bacteria was obtained by indirect
observation, namely through laboratory tests and data collection
techniques using the ANOVA test with an error rate (0.05) and followed by
the Tukkey HSD test through the SPSS16.0 program. Based on the results
of the antibacterial test of breadfruit leaf juice (Artocarpus altilis) in the
ANOVA test, the probability number was 0.000 and there was an effect on
the growth of Staphylococcus aureus bacteria. Followed by the Tukkey HSD
test, it was obtained at a concentration of 25% which is the minimum
inhibitory power, the effective concentration to inhibit the growth of
Staphylococcus aureus at a concentration of 75%. From the data above, it
can be concluded that there is an effect of breadfruit leaf juice (Artocarpus
altilis) on the growth of Staphylococcus aureus.
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Keywords: Artocarpus altilis, Breadfruit Leaf, Staphylococcus aureus